>> HOMEPAGE

AIDS Research

Micronutrients and HIV-1 disease progression.

AIDS 1995 Sep;9(9):1051-6 (ISSN: 0269-9370)

Baum MK; Shor-Posner G; Lu Y; Rosner B; Sauberlich HE; Fletcher MA; Szapocznik J; Eisdorfer C; Buring JE; Hennekens CH Department of Epidemiology and Public Health, University of Miami School of Medicine, Florida 33101, USA.

OBJECTIVE: To determine whether nutritional status affects immunological markers of HIV-1 disease progression. DESIGN: A longitudinal study, to evaluate the relationship between plasma levels of nutrients and CD4 cell counts, along and in combination with beta 2-microglobulin (beta 2M; AIDS index) over an 18-month follow-up. METHODS: Biochemical measurements of nutritional status including plasma proteins, zinc, iron and vitamins B1, B2, B6, B12 (cobalamin), A, E, C and folate and immunological markers [lymphocyte subpopulations (CD4) and beta 2M] were obtained in 108 HIV-1-seropositive homosexual men at baseline and over three 6-month time periods. Changes in nutrient status (e.g., normal to deficient, deficient to normal), were compared with immunological parameters in the same time periods using an autoregressive model. RESULTS: Development of deficiency of vitamin A or vitamin B12 was associated with a decline in CD4 cell count (P = 0.0255 and 0.0377, respectively), while normalization of vitamin A, vitamin B12 and zinc was associated with higher CD4 cell counts (P = 0.0492, 0.0061 and 0.0112, respectively). These findings were largely unaffected by zidovudine use. For vitamin B12, low baseline status significantly predicted accelerated HIV-1 disease progression determined by CD4 cell count (P = 0.041) and the AIDS index (P = 0.005). CONCLUSIONS: These data suggest that micronutrient deficiencies are associated with HIV-1 disease progression and raise the possibility that normalization might increase symptom-free survival.

Sitemap

Was ist neu:

Lehren aus der tödlichen Viagra-Studie an Schwangeren: Sichere, natürliche Alternativen sollten bei klinischen Versuchen Vorrang haben

Gates-Stiftung unterstützt Plan zur globalen „Harmonisierung von Nährstoffgrenzen“ in Ergänzungsmitteln

Natürliche Behandlung von Immunschwächekrankheiten

Die Geschichte des Pharma-Kartells

Mikronährstoffe können vor Zellschäden durch Strahlung schützen

Bildgebende Diagnostik kann in Zellen Strahlungsschäden verursachen

Erhöhte Cholesterinspiegel natürlich senken, ohne Medikamente

Herzrhythmusstörungen auf natürliche Weise vorbeugen bzw. korrigieren

Niereninsuffizienz und deren natürlicher Behandlungsansatz

ADHS natürlich behandeln

» Natürliche Gesundheit

» "Geschäft m. d. Krankheit"

» Internationale Kampagne

» Dr. Raths Offene Briefe

» Studien weltweit

» Studien auf Deutsch

» Helfen Sie mit!

» Codex Alimentarius

» Dossiers

» Sitemap

Dr. Rath Health Foundation auf Facebook Dr. Rath Health Foundation auf YouTube Dr. Rath Health Foundation auf Twitter RSS
 © 2018 Dr. Rath Health Foundation | Kontakt | Impressum | Nutzungsbedingungen | Datenschutzerklärung | RSS Feed