>> HOMEPAGE

AIDS Research

Status of selected nutrients and progression of human immunodeficiency virus type 1 infection.

Am J Clin Nutr 2000 Sep;72(3):809-15 (ISSN: 0002-9165)

Bogden JD; Kemp FW; Han S; Li W; Bruening K; Denny T; Oleske JM; Lloyd J; Baker H; Perez G; Kloser P; Skurnick J; Louria DB Department of Preventive Medicine and Community Health, the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark.bogden@umdnj.edu.

BACKGROUND: Immune function is highly dependent on nutritional status because the large mass and high rate of cellular turnover of the immune system make it a major user of nutrients. Furthermore, nutrient requirements may be increased during acute and chronic infections, including HIV-1 infection. OBJECTIVE: The current study was designed to assess relations among HIV-1 progression and 11 nutritional and demographic variables. DESIGN: The participants were 106 HIV-infected outpatients and 29 uninfected control subjects (n = 89 men and 46 women; age range: 35-57 y). The HIV-infected subjects represented a broad range of disease progression. RESULTS: We found lower concentrations of plasma and erythrocyte magnesium and of erythrocyte reduced glutathione beginning early in the course of HIV-1 infection. Significantly decreased hematocrit and increased serum copper concentration developed only late in the course of the disease. Statistically significant univariate associations were found between the CD4(+) T lymphocyte count and hematocrit, plasma magnesium concentration, and plasma zinc concentration. The lowest erythrocyte magnesium concentrations occurred in HIV-infected subjects who consumed alcoholic beverages. Independent variables that were significant joint predictors of CD4(+) cell count in multiple regression analyses were hematocrit and plasma free choline and zinc concentrations. These 3 factors together explained 43% of the variability in CD4(+) cell counts. CONCLUSION: The results provide evidence that compromised nutritional and antioxidant status begin early in the course of HIV-1 infection and may contribute to disease progression.

Sitemap

Was ist neu:

Professor der Stanford Universität sieht Zusammenbruch des Öl-Kartells näher rücken

Bereits einwöchiger Gebrauch üblicher Schmerzmittel steigert das Risiko auf Herzinfarkt

Neue klinische Übersichtsarbeit erkennt in Sonnenschutzmitteln die Ursache für weit verbreiteten Vitamin D-Mangel

Aufsichtsbehörden der Brüsseler EU ignorieren unverhohlen die Giftwirkungen von Pestizid-Cocktails in Nahrungsmitteln

Internationales Tribunal bezichtigt Monsanto des ›Ökozids‹

Wer weiß, was das Beste für Ihre Kinder ist? Sie? Oder die Regierung?

Daueranwendung von Antibiotika kann Darmkrebs-Risiko erhöhen

Niedergang der Brüsseler EU rückt näher

David Rockefeller mit 101 verstorben: Nachrufe in den Medien unterschlagen seine zentrale Rolle in der Bilderberg-Gruppe

Hochdosierte B-Vitamine haben laut Studie Schutzwirkung gegen verschmutzte Luft

Neue Hiobsbotschaften für die Pharma: Bisphosphonat-Medikamente gegen Osteoporose SCHWÄCHEN die Knochen!

>> Natürliche Gesundheit

>> "Geschäft m. d. Krankheit"

>> Internationale Kampagne

>> Dr. Raths Offene Briefe

>> Studien weltweit

>> Studien auf Deutsch

>> Helfen Sie mit!

>> Codex Alimentarius

>> Dossiers

>> Sitemap

Dr. Rath Health Foundation auf Facebook Dr. Rath Health Foundation auf YouTube Dr. Rath Health Foundation auf Twitter RSS
 © 2017 Dr. Rath Health Foundation | Kontakt | Impressum | RSS Feed