Coutinho EM; de Freitas LP; Abath FG
The influence of the regional basic diet from northeast Brazil on health
and nutritional conditions of mice infected with Schistosoma mansoni.
Rev Soc Bras Med Trop 1992 Jan-Mar;25(1):13-20
status indicators were studied in weanling albino Swiss mice infected
with S. mansoni and fed the Regional Basic Diet (RBD) from Northeast Brazil,
a multi-deficient diet of low-protein content. Each mouse was infected
percutaneously with 80 cercariae. The experiment lasted 63 days. The growth
curve, food consumption, protein intake, weight gain, Protein Efficiency
Ratio (PER) and Net Protein Ratio (NPR) were the parameters investigated.
RBD-fed mice showed a marked weight loss, a lower food and protein intake,
a slower body weight gain and lower rates of food protein utilization
when compared to casein-fed animals. Differences between infected and
non-infected mice were not consistent. The present results suggest
that the effects of RBD-induced malnutrition on health and nutritional
conditions of the mice are more severe than those of Manson's schistosomiasis,
in the initial phase of the disease.